王青山:大連醫科大學教授-中文百科頻道

人物經曆

1998年-2003年：山東大學衛生檢驗專業醫學學士

2003年-2006年：山東大學衛生毒理專業醫學碩士

2006年-2009年：山東大學衛生毒理專業醫學博士

2009年-2015年：美國國立衛生研究院博後、研究員

2015年-至今：大連醫科大學教授教研室主任

主要成就

科研成就

論文

1.Wang Q*, Qian L, Chen SH, Chu CH, Wilson B, Esteban O, Ali S, Robinson B, Rao D, Hong JS*. Post-treatment with an ultra-low dose of NADPH oxidase inhibitor diphenyleneiodonium attenuates disease progression in multiple Parkinson’s disease models. Brain. 2015, 138(Pt 5):1247-62. (IF: 11.814)

2.Hou L, Sun F, Huang R, Sun W, Zhang D, Wang Q*. Inhibition of NADPH oxidase by apocynin prevents learning and memory deficits in a mouse Parkinson's disease model. Redox Biol. 2019, 22:101134. (IF: 7.793)

3.Hou L, Bao X, Zang C, Yang H, Sun F, Che Y, Wu X, Li S, Zhang D, Wang Q*. Integrin CD11b mediates α-synuclein-induced activation of NADPH oxidase through a Rho-dependent pathway. Redox Biol. 2018, 14:600-608. (IF: 7.793)

4.Hou L, Wang K, Zhang C, Sun F, Che Y, Zhao X, Zhang D, Li H, Wang Q*. Complement receptor 3 mediates NADPH oxidase activation and dopaminergic neurodegeneration through a Src-Erk-dependent pathway. Redox Biol. 2018, 14:250-260. (IF: 7.793)

5.Hou L, Zhou X, Zhang C, Wang K, Liu X, Che Y, Sun F, Li H, Wang Q*, Zhang D*, Hong JS. NADPH oxidase-derived H2O2 mediates the regulatory effects of microglia on astrogliosis in experimental models of Parkinson’s disease. Redox Biol. 2017. 12:162-170. (IF: 7.793)

6.Wang Q*, Song S, Esteban O, Santio J, Wilson B, Hong JS. Locus coeruleus neurons are most sensitive to chronic neuroinflammation-induced neurodegeneration. Brain Behav Immun. 2020, doi: 10.1016/j.bbi.2020.01.003. (IF: 6.170)

7.Hou L, Zhang L, Hong JS, Zhang D*, Zhao J*, Wang Q*. NADPH oxidase and neurodegenerative diseases: mechanisms and therapy. Antioxid Redox Signal. 2020 Jan 22. doi: 10.1089/ars.2019.8014. (IF: 5.828)

8.Wang Q*, Chu CH, Qian L, Chen SH, Wilson B, Oyarzabal E, Jiang L, Ali S, Robinson B, Kim HC, Hong JS*. Substance P exacerbates dopaminergic neurodegeneration through neurokinin-1 receptor-independent activation of microglial NADPH oxidase. J Neurosci. 2014, 34(37):12490-503. (IF: 6.074)

9.Jiang L, Chen S, Chu C, Wang S, Esteban O, Wilson B, Sanders V, Xie K, Wang Q*, Hong J*. A novel role of microglial NADPH oxidase in mediating extra-synaptic function of norepinephrine in regulating brain immune homeostasis. Glia. 2015, 63(6):1057-72. (IF: 5.829)

10.Che Y, Hou L, Sun F, Zhang C, Liu X, Piao F, Zhang D, Li H, Wang Q*. Taurine protects dopaminergic neurons in a mouse Parkinson’s disease model through inhibition of microglial M1 polarization. Cell Death Dis. 2018, 9(4):435. (IF: 5.959)