人物經曆
教育背景
2003年9月-2007年6月,南京農業大學,水産養殖學,農學學士;
2007年9月-2011年11月,中國科學院水生生物研究所,水生生物學,理學博士;
工作經曆
2012年1月-2015年12月,中國科學院水生生物研究所,助理研究員;
2014年8月-2015年8月,美國密歇根大學,博士後;
2015年12月至今,中國科學院水生生物研究所,副研究員;
主要成就
科研成就
科研項目
(1)三種四膜蟲全基因組N6-甲基腺嘌呤的鑒定及其功能進化,主持,國家級,2017-01--2020-12
(2)中國科學院青年創新促進會會員人才專項,主持,部委級,2016-01--2019-12
(3)中國科學院知識創新工程青年人才領域前沿項目,主持,市地級,2014-01--2015-12
(4)模式生物嗜熱四膜蟲轉錄組數據庫建設,主持,院級,2014-01--2015-12
(5)模式原生動物嗜熱四膜蟲DNA複制起點的鑒定及其特征分析,主持,國家級,2014-01--2016-12
(6)原生動物四膜蟲生殖小核(germlinenucleus)體功能(somaticfunction)的分子基礎研究,主持,國家級,2019-01--2021-12
論文著作
(1) Single-cell transcriptome sequencing of rumen ciliates provides insight into their molecular adaptations to the anaerobic and carbohydrate-rich rumen microenvironment, Molecular phylogenetics and evolution, 2020, 第 7 作者
(2) Sexual cell cycle initiation is regulated by CDK19 and CYC9 in Tetrahymena thermophila, Journal of Cell Science, 2020, 第 5 作者
(3) Proteomic identification and expression of oral apparatus constituents in cell regeneration of giant ciliate Stentor coeruleus (strain WHEL), Gene, 2020, 第 5 作者
(4) Tetrahymena Comparative Genomics Database (TCGD): a community resource for Tetrahymena, Database, 2019, 第 8 作者
(5) Insights into the origin and evolution of Peritrichia (Oligohymenophorea, Ciliophora) based on analyses of morphology and phylogenomics, Molecular phylogenetics and evolution, 2019, 第 3 作者
(6) RNAi-dependent Polycomb repression controls transposable elements in Tetrahymena, Genes & development, 2019, 第 2 作者
(7) Hidden genomic evolution in a morphospecies—The landscape of rapidly evolving genes in Tetrahymena, PLoS biology, 2019, 第 1 作者
(8) Exploration of Genetic Variations through Single‐cell Whole‐genome Sequencing in the Model Ciliate Tetrahymena thermophila, Journal of Eukaryotic Microbiology, 2019, 第 3 作者
(9) 進展中的原生動物學研究:熱點領域與新格局, Progress of protozoological studies in China: Hot spots and new patterns, 中國科學:生命科學, 2019, 第 1 作者
(10) xploration of Genetic Variations through Single‐cell Whole‐genome Sequencing in the Model Ciliate Tetrahymena thermophila, Journal of Eukaryotic Microbiology, 2019, 第 3 作者
(11) EOGD: the Euplotes octocarinatus genome database, BMC Genomics, 2018, 第 4 作者
(12) A DP-like transcription factor protein interacts with E2fl1 to regulate meiosis in Tetrahymena thermophila, Cell cycle, 2018, 第 5 作者
(13) Pseudocohnilembus persalinus genome database-the first genome database of facultative scuticociliatosis pathogens, BMC genomics, 2018, 第 5 作者
(14) A germline-limited piggyBac transposase gene is required for precise excision in Tetrahymena genome rearrangement, Nucleic Acids Research, 2017, 第 4 作者
(15) Dissecting relative contributions of cis-and trans-determinants to nucleosome distribution by comparing Tetrahymena macronuclear and micronuclear chromatin, Nucleic Acids Research, 2016, 第 1 作者
(16) Epidermal growth factor-induced stimulation of proliferation and gene expression changes in the hypotrichous ciliate, Stylonychia lemnae, Gene, 2016, 通訊作者
(17) 四膜蟲功能基因組數據庫增量更新 2016-生活史和減數分裂轉錄組及磷酸化蛋白組資源建設, 基因組學與應用生物學, 2016, 通訊作者
(18) Tracing the structural evolution of eukaryotic ATP binding cassette transporter superfamily, Scientific reports, 2015, 第 1 作者
(19) Genome of the facultative scuticociliatosis pathogen Pseudocohnilembus persalinus provides insight into its virulence through horizontal gene transfer, Scientific reports, 2015, 第 1 作者
(20) The genome of the myxosporean Thelohanellus kitauei shows adaptations to nutrient acquisition within its fish host, Genome biology and evolution, 2014, 第 2 作者
(21) Impaired replication elongation in Tetrahymena mutants deficient in histone H3 Lys 27 monomethylation, Genes & development, 2013, 第 2 作者
(22) Tetrahymena functional genomics database (TetraFGD): an integrated resource for Tetrahymena functional genomics, Database, 2013, 第 1 作者
(23) Transcriptome analysis of the model protozoan, Tetrahymena thermophila, using deep RNA sequencing, PLoS One, 2012, 第 1 作者
(24) Tetrahymena Gene Expression Database (TGED): a resource of microarray data and co-expression analyses for Tetrahymena, Science China Life sciences, 2011, 第 1 作者
(25) Gene network landscape of the ciliate Tetrahymena thermophila, PloS one, 2011, 第 1 作者
(26) Genome-wide identification and evolution of ATP-binding cassette transporters in the ciliate Tetrahymena thermophila: A case of functional divergence in a multigene family, BMC evolutionary biology, 2010, 第 1 作者
人才培養
現指導碩士研究生1人
榮譽表彰
中國動物學會原生動物學分會青年科技獎,其他,2017
青年科技獎,一等獎,研究所(學校),2016
湖北省優秀博士論文獎,一等獎,省級,2013
社會任職
中國科學院青年創新促進會會員