人物經曆
1991年德國達姆施達特技術大學獲博士學位
1991年至1999年先後在德國盧卑克醫科大學博士後
2000年12月至今中國科學院上海矽酸鹽所研究員。
主要成就
科研成就
代表性論文
Zhaowenbin Zhang, Qiuxia Dai, Yu Zhang, Hui Zhuang, Endian Wang, Qing Xu, Lingling Ma, Chengtie Wu, Zhiguang Huan, Feng Guo,* and Jiang Chang*, Design of a Multifunctional Biomaterial Inspired by Ancient Chinese Medicine for Hair Regeneration in Burned Skin, ACS Appl. Mater. Interfaces 2020, 12, 12489-12499.
Lingling Ma, Yanling Zhou, Zhaowenbin Zhang, Yaqin Liu, Dong Zhai, Hui Zhuang, Qin Li, Jianding Yuye, Chengtie Wu, Jiang Chang*. Multi-functional Bioactive Nd-Ca-Si Glasses for Fluorescent Thermometry, Photothermal Therapy and Burn Tissue Repair. Science Advances 2020, ln Press
Qing Xu, Mengling Chang, Yu Zhang, Endian Wang, Min Xing, Long Gao, Zhiguang Huan, Feng Guo, Jiang Chang*. PDA/Cu bioactive hydrogel with “hot ions effect” for inhibition of drug-resistant bacteria and enhancement of infectious skin wound healing. ACS Applied Materials & Interfaces 2020, ln Press
Feng Bao, Ge Pei, Zhongcao Wu, Hui Zhuang, Zhaowenbin Zhang, Zhiguang Huan, Chengtie Wu and Jiang Chang*, Bioactive self-pumping composite wound dressings with micropore array modified Janus membrane for enhanced diabetic wound healing, Advanced Fanctional Materials, 2020, in press.
Yanling Zhou, Chengtie Wu, Jiang Chang*, Bioceramics to regulate stem cells and their microenvironment for tissue regeneration, Materials Today, 2019 (20), 41-56.
Yu Zhang, Mengling Chang, Feng Bao, Min Xing, Endian Wang, Qing Xu, Zhiguang Huan, Feng Guo* and Jiang Chang*, Multifunctional Zn doped hollow mesoporous silica/polycaprolactone electrospun membranes with enhanced hair follicle regeneration and antibacterial activity for wound healing, Nanoscale, 2019, 11, 6315–6333
Hongshi Ma,# Quan Zhou,# Jiang Chang, Chengtie Wu*. Grape Seed-Inspired Smart Hydrogel Scaffolds for Melanoma Therapy and Wound Healing. ACS Nano 2019,13(4):4302-4311.
Tian Li, Dong Zhai, Bing Ma, Jianmin Xue, Pengyu Zhao, Jiang Chang, Michael Gelinsky, Chengtie Wu*.3D Printing of Hot Dog-Like Biomaterials with Hierarchical Architecture and Distinct Bioactivity. Advanced Science 2019, 1901146 (1-8).
Lei Chen#, Cuijun Deng#, Jiayi Li, Qingqiang Yao*, Jiang Chang*, Liming Wang, Chengtie Wu*.3D printing of a lithium-calcium-silicate crystal bioscaffold with dual bioactivities for osteochondral interface reconstruction. Biomaterials 2019，196:138-150.
Min Yi#, Hekai Li#, Xiaoya Wang, Jianyun Yan, Long Gao, Yinyan He, Xinglong Zhong, Yanbin Cai, Weijing Feng, Zhanpeng Wen, Chengtie Wu, Caiwen Ou*, Jiang Chang*, Minsheng Chen*. Ion Therapy: A Novel Strategy for Acute Myocardial Infarction. Advanced Science. 2019,6(1):1801260 (1-17).
Chen Yang, Cancan Zhao, Xiaoya Wang, Mengchao Shi, Yanlun Zhu, Linguo Jing, Chengtie Wu, Jiang Chang*. Stimulation of Osteogenesis and Angiogenesis by Micro/Nano Hierarchical Hydroxyapatite via Macrophage Immunomodulation. Nanoscale. 2019,11:17699–17708.
Long Gao, Yanling Zhou, Jinliang Peng, Chen Xu, Qing Xu, Min Xing, Jiang Chang*. A Novel Dual-adhesive and Bioactive Hydrogel Activated by Bioglass for Wound Healing. NPG Asia Materials 2019,11：66（1-11）
Chen Xu, Bing Ma, Jinliang Peng, Long Gao, Yuhong Xu, Zhiguang Huan, Jiang Chang*. Tricalcium silicate/graphene oxide bone cement with photothermal properties for tumor ablation. Journal of Materials Chemistry B. 2019, 7:2808-2818.
Yanlun Zhu#, Lingzhi Kong#, Fatemeh Farhadi, Wei Xia, Jiang Chang, Yaohua He*, Haiyan Li*. An injectable continuous stratified structurally and functionally biomimetic construct for enhancing osteochondral regeneration. Biomaterials 2019, 192:149–158.
Xiaoya Wang, Long Gao, Yan Han, Min Xing, Cancan Zhao, Jinliang Peng, and Jiang Chang*, Silicon-Enhanced Adipogenesis and Angiogenesis for Vascularized Adipose Tissue Engineering, Advanced Science. 2018,1800776
Yu Zhang, Cui Huang,* and Jiang Chang,* Ca-doped mesoporous SiO2/dental resin composites with enhanced mechanical properties, bioactivity and antibacterial properties, Journal of Materials Chemistry B 2018, 6:477-486
Yan Huang #, Chengtie Wu #, Xiaoling Zhang, Jiang Chang* Kerong Dai*. Regulation of immune response by bioactive ions released from silicate bioceramics for bone regeneration. Acta Biomaterialia 2018, 66:81-92.
Yang Zhou, Yanling Zhou, Long Gao, Chengtie Wu, Jiang Chang*, Synthesis of artificial dental enamel by an elastin-like polypeptide assisted biomimetic approach. Journal of Materials Chemistry B. 2018,6:844-853
Chen Xu, XiaoYa Wang, Jie Zhou, Zhiguang Huan*, Jiang Chang*, Bioactive tricalcium silicate/alginate composite bone cements with enhanced physicochemical properties. Journal of Biomedical Materials Research: Part B - Applied Biomaterials, 2018, 106B:237-244
Yanling Zhou, Chen Xua, Xiaoya Wang, Yuandong Dou, Zhiguang Huan*, Jiang Chang*, Fast setting tricalcium silicate/magnesium phosphate premixed cement for root canal filling. Ceramics International. 2018,44:3015-3023
Chen Yang, Zhiguang Huan, Xiaoya Wang, Chengtie Wu, Jiang Chang*. 3D Printed Fe Scaffolds with HA Nanocoating for Bone Regeneration. ACS Biomaterials Science & Engineering. 2018,4:608-616
Cancan Zhao, Xiaoya Wang, Long Gao, Linguo Jing, Quan Zhou, Jiang Chang*. The role of the micro-pattern and nano-topography of hydroxyapatite bioceramics on stimulating osteogenic differentiation of mesenchymal stem cells. Acta Biomaterialia 2018,73: 509–521
Min Xing, Xiaoya Wang, Endian Wang, Long Gao, Jiang Chang*. Bone tissue engineering strategy based on the synergistic effects of silicon and strontium ions. Acta Biomaterialia 2018, 72: 381–395
Yanling Zhou, Long Gao, Jinliang Peng, Min Xing, Yan Han, Xiaoya Wang, Yuhong Xu, Jiang Chang*. Bioglass Activated Albumin Hydrogels for Wound Healing. Advanced Healthcare Materials 2018, 1800144
Shuo Chen, Zhiguang Huan, Lin Zhang*, Jiang Chang*. The clinical application of a silicate-based wound dressing (DermFactor) for wound healing after anal surgery: A randomized study. International Journal of Surgery 2018, 52:229–232
Xiaocheng Wang#, Tao Li#, Hongshi Ma, Dong Zhai, Chuan Jiang, Jiang Chang,* Jinwu Wang,* Chengtie Wu*. A 3D-Printed scaffold with MoS2 nanosheets for tumor therapy and tissue regeneration. NPG Asia Materials 2017,9:376-389
Chen Yang, Xiaoya Wang, Bing Ma, Zhiguang Huan, Nan Ma, Haibo Zhu, Chengtie Wu, and Jiang Chang*, 3D-printed bioactive Ca3SiO5 bone cement scaffolds with nano surface structure for bone regeneration, ACS Applied Materials & Interfaces 2017,9:5757-5767
Yachen Xu, Jinliang Peng, Xin Dong, Yuhong Xu, Haiyan Li*, Jiang Chang*. Combined chemical and structural signals of biomaterials synergistically activates cell-cell communications for improving tissue regeneration. Acta Biomaterialia, 2017,55: 249-261
Yonghui Li#, Yan Han#, Xiaoya Wang, Jinliang Peng, Yuhong Xu, Jiang Chang*. Multi-functional hydrogels prepared by dualion crosslinking for chronic wound healing. ACS Applied Materials & Interfaces.2017,9(19):16054-16062
Yan Han#, Yonghui Li#, Qiongyu Zeng, Haiyan Li, Jinliang Peng, Yuhong Xu, Jiang Chang*. Injectable bioactive akermanite/alginate composite hydrogels for in situ skin tissue engineering. Journal of Materials Chemistry B. 2017, 5(18) :3315-3326
Lunguo Xia, Zhilan Yin, Lixia Mao, Xiuhui Wang, Jiaqiang Liu, Xinquan Jiang, Zhiyuan Zhang, Kaili Lin*, Jiang Chang*, Bing Fang*, Akermanite bioceramics promote osteogenesis, angiogenesis and suppress osteoclastogenesis for osteoporotic bone regeneration, Scientific Reports, 2016 ,6:22005.
Haiyan Li, Jin He, Hongfei Yu, Colin R Green*, Jiang Chang*, Bioglass promotes wound healing by affecting gap junction connexin 43 mediated endothelial cell behavior, Biomaterials, 2016,84:64-75
Hongshi Ma, Chuan Jiang, Dong Zhai, Yongxiang Luo, Yu Chen, Fang Lv, Zhengfang Yi, Yuan Deng, Jinwu Wang, Jiang Chang,* Chengtie Wu*. A bifunctional biomaterial with photothermal effect for tumor therapy and bone regeneration. Advanced Functional Materials. 2016,26(8):1197-1208
Xixi Dong#, Haiyan Li#, Yanling Zhou, Long Ou, Junkai Cao, Jiang Chang*. The stimulation of osteogenic differentiation of embryoid bodies from human induced pluripotent stem cells by akermanite bioceramics. J Mater Chem B, 2016, 4, 2369-2376.
Fangfang Wang, Dong Zhai, Chengtie Wu*, Jiang Chang*. Multifunctional mesoporous bioactive glass/UCNPs nanocomposites with strong red emission for monitoring drug delivery and stimulating osteogenic differentiation of stem cells. Nano Research 2016, 9(4):1193-1208
Chengtie Wu,* Lunguo Xia, Pingping Han, Lixia Mao, Jiacheng Wang, Dong Zhai, Bing Fang*, Jiang Chang*, Yin Xiao. Europium (Eu)-containing mesoporous bioactive glass scaffolds for stimulating in vitro and in vivo osteogenesis. ACS Appl Mater Interface 2016,8:11342–11354
Lunguo Xia, Na Zhang, Xiuhui Wang, Yuning Zhou, Lixia Mao, Jiaqiang Liu, Xinquan Jiang, Zhiyuan Zhang, Jiang Chang,* Kaili Lin*, Bing Fang*. The synergetic effect of nano-structures and silicon-substitution on the properties of hydroxyapatite scaffolds for bone regeneration. Journal of Materials Chemistry B, 2016, 4:3313-3323
榮譽表彰
曾獲新西蘭華人傑出貢獻獎（1996年）
上海市科技進步二等獎（2006年）
第一屆長甯區領軍人才（2007年）
全國歸僑僑眷先進個人（2009年）
第四屆中國僑界貢獻獎（創新人才）（2012）
中國科學院朱李月華優秀教師獎（2012年）
第六屆中國僑界貢獻獎（創新團隊）（2016）
中國生物材料學會科學技術一等獎（2019）
社會任職
國際生物材料學會聯合會會士(Fellow),英國皇家化學會會士(Fellow),美國醫學與生物工程院會士（Fellow），國際可注射骨和關節生物材料學會副主席，國家自然基金委醫學部第三/四屆專家咨詢委員會委員，中國生物材料學會常務理事。全國外科植入物和矯形器械标準化技術委員會組織工程醫療器械産品分技委委員。國際學術期刊“材料化學B”（Journal of Materials Chemistry B）副主編， Biomaterials編委。
