陈兴:北京大学化学与分子工程学院教授-中文百科频道

人物经历

2017–至今北大-清华生命科学联合中心高级研究员

2016–至今北京大学化学与分子工程学院教授

2011–至今北京大学合成与功能生物分子中心研究员

2011–2017北大-清华生命科学联合中心研究员

2010–2016北京大学化学与分子工程学院研究员

2007–2010哈佛大学医学院博士后

2007加州大学伯克利分校化学博士

2002清华大学化学学士

主要成就

科研成就

论文

Qin, W.; Lv, P.; Fan, X.; Quan, B.; Zhu, Y.; Qin, K.; Chen, Y.; Wang, C.; Chen, X. “Quantitative Time-Resolved Chemoproteomics Reveals Stable O-GlcNAc Regulates Box C/D snoRNP Biogenesis” Proc. Natl. Acad. Sci. USA 114, E6749-E6758 (2017).

Xie, R.; Dong, L.; Du, Y.; Zhu, Y.; Hua, R.; Zhang, C.; Chen, X. “In Vivo Metabolic Labeling of Sialoglycans in the Mouse Brain By Using A Liposome-Assisted Bioorthogonal Reporter Strategy” Proc. Natl. Acad. Sci. USA 113, 5173-5178 (2016).

Zhu, Y.; Wu, J.; Chen, X. “Metabolic Labeling and Imaging of N-Linked Glycans in Arabidopsis Thaliana” Angew. Chem. Int. Ed 55, 9301-9305 (2016).

Lin, L.; Liu, L.; Zhao, B.; Xie, R.; Lin, W.; Li, H.; Shi, M.; Chen, Y.; Springer, T. A.; Chen, X. “Carbon Nanotube-Assisted Optical Activation of TGF- Signaling by Near-Infrared Light” Nature Nanotech. 10, 465-471 (2015).

Xie, R.; Dong, L.; Huang, R.; Hong, S.; Lei, R.; Chen, X. “Targeted Imaging and Proteomic Analysis of Tumor-Associated Glycans in Living Animals” Angew. Chem. Int. Ed. 53, 14082-14086 (2014).

Hong, S.; Chen, T.; Zhu, Y.; Li, A.; Huang, Y.; Chen, X. “Live-Cell Stimulated Raman Scattering Imaging of Alkyne-Tagged Biomolecules” Angew. Chem. Int. Ed. 53, 5827-5831 (2014).

Lin, W.; Du, Y.; Zhu, Y.; Chen, X. “A Cis-Membrane FRET-Based Method for Protein-specific Imaging of Cell-Surface Glycans” J. Am. Chem. Soc. 136, 679-687 (2014).

Feng, L.; Hong, S.; Rong, J.; You, Q.; Dai, P.; Huang, R.; Tan, Y.; Hong, W.; Xie, C.; Zhao, J.; Chen, X. “Bifunctional Unnatural Sialic Acids for Dual Metabolic Labeling of Cell-Surface Sialylated Glycans” J. Am. Chem. Soc. 135, 9244-9247 (2013).

Lin, L.; Tian, X.; Hong, S.; Dai, P.; You, Q.; Wang, R.; Feng, L.; Xie, C.; Tian, Z.; Chen, X. “A Bioorthogonal Raman Reporter Strategy for SERS Detection of Glycans on Live Cells” Angew. Chem. Int. Ed. 52, 7266-7271 (2013).

Xie, R.; Hong, S.; Feng, L.; Rong, J.; Chen, X. “Cell-Selective Metabolic Glycan Labeling Based on Ligand-Targeted Liposomes” J. Am. Chem. Soc. 134, 9914-9917 (2012).