刘宇:辽宁大学药学院副院长-中文百科频道

人物经历

2011年毕业于沈阳药科大学药剂学专业并取得博士学位。

主要成就

参与项目

国家青年基金项目，81503024、基于多功能电解质修饰的氧化石墨烯作为抗癌药物口服缓控释载体的制备及其胃肠道转运机制研究、21.5万元、在研、主持。

辽宁省教育厅项目，L2013011、丁酸氯维地平纳米乳注射液的研制、2013/09-2016/08、3万元、在研、主持。

辽宁省教育厅项目，L2014006、酮洛芬经皮给药纳米晶递药系统的构建及透过机理研究、2014/01-2017/01、6万元、在研，参与。

辽宁省科技厅，2013305003、治疗肺癌靶向药物--蓓萨罗丁纳米结晶制剂研制与开发、2013/10-2016/10、20万元、在研、参与。

辽宁“百千万人才工程”人选资助项目，2013305003、藤黄酸脂微球的研制与开发、2012/12-2015/12、10万元、在研、参与。

辽宁省科技厅项目，20092015、赤芍总苷的制备及其渗透泵控释给药系统的研究、2009/01-2012/01、10万元、已结题、参与。

学术论文

1.Yu Liu, SunDong Yoo, Li Li, Liang Fang, Ziyi Wen and Tiefu Li. Formulation and characterization of boanmycin-loaded liposomes prepared by pH gradient experimental design. Drug Delivery, 2012, 19, 90-101.

2.Yu Liu, SunDong Yoo, Liang Fang, Xin Jin, Li Li, YanJun Ren, ChongShun Yao, TieFu Li. Determination of boanmycin in pharmaceutical preparations by a simple and rapid ion-pair LC method. Chromatographia, 2009, 70，643.

3.Yu Liu, SunDong Yoo, Liang Fang, Xin Jin, Li Li, Tiefu Li. Ion-pair LC–UV method for the determination of boanmycin in mouse plasma and its application to a pharmacokinetic study. Chromatographia, 2010, 72, 357–359.

4. Li Li, Xiaoyang Yang,Yu Liu*, Lijiang Chen, Xin Jin. Studies on pharmacokinetics and tissue distribution of curcumol liposome. Lat. Am. J. Pharm., 2014, 33: 709-716.

5.Yu Liu, Jia Yang, Ju Liu, Zhaobo Wang, Hongsheng Liu＆Lijiang Chen. In vitro and in vivo evaluation of redox-responsive sorafenib carrier nanomicells synthesized from poly(acryic acid)-cystamine hydrochloride-D-a-tocopherol succinate. Journal of Biomaterials Science, Polymer Edition. 2016, 27(17): 1729-1747.

6.Yongjie Wang, Jinghong Rong, Jiaozhen Zhang,Yu Liu, Xuelian Meng, Hejian Guo, Hongsheng Liu, Lijiang Chen. Morphology, in vivo distribution and antitumor activity of bexarotene nanocrystals in lung cancer. Drug Development and Industrial Pharmacy.

7.Li Li,Yu Liu, Jinjing Wang, Lijiang Chen,Wenjun Zhang, Xichen Yan. Preparation in vitro and in vivo evaluation of bexarotene nanocrystals with surface modification by folate-chitosan conjugates. Drug Deliv, 2016, 23(1): 79-87.

8.Li Li,Yu Liu, Xin Wang, Yang Liu, Jinjing Wang, Lijiang Chen.Studies onpharmacokinetics and tissue distribution of bexarotenenanocrystals with surface modification by folate-chitosan conjugates, Latin American Journal of Pharmacy, 2015, 34(4): 712-718.

9. Li Li, Jijun Liang,Yu Liu, Lijiang Chen, Wenjun Zhang, En Lu. Simultaneous Determination of Luteolin and Ayanin in Rat Plasma by HPLC-MS-MS and its Application in a Pharmacokinetic Study, Latin American Journal of Pharmacy, 2014, 33(9): 1475-1480.

10. Rui Yan, Longmei Qu, NanLuo, Yang Liu,Yu Liu, Li Li, Chen Lijiang. Quantitation of alpha-Lactalbumin by Liquid Chromatography Tandem Mass Spectrometry in Medicinal Adjuvant Lactose, Int J Anal Chem, 2014, 2014: 841084-841084.

11. Chen Li-jiang, Liu Yang,Liu Yu, Li Li, Gao Fei. Enhanced bioavailability of total paeony glycoside by self-microemulsifying drug delivery system, European Journal of Medicinal Chemistry, 2012, 47(12): 1678-1686.